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Paolo Santambrogio Selected Research

Apoferritins

12/2021H-Ferritin Produced by Myeloid Cells Is Released to the Circulation and Plays a Major Role in Liver Iron Distribution during Infection.
4/2021Pathogenic mechanism and modeling of neuroferritinopathy.
11/2019Stem Cell Modeling of Neuroferritinopathy Reveals Iron as a Determinant of Senescence and Ferroptosis during Neuronal Aging.
4/2017Unexplained isolated hyperferritinemia without iron overload.
3/2014Iron availability is increased in individual human ovarian follicles in close proximity to an endometrioma compared with distal ones.
8/2013Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome.
1/2013Mycobacterium avium infection induces H-ferritin expression in mouse primary macrophages by activating Toll-like receptor 2.
4/2010Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation.
3/2009Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells.
1/2007Analysis of ferritin genes in Parkinson disease.
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Paolo Santambrogio Research Topics

Disease

5Movement Disorders (Movement Disorder)
04/2021 - 09/2006
5Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease)
12/2020 - 09/2012
4Neuroferritinopathy
04/2021 - 09/2006
4Friedreich Ataxia (Friedreich's Ataxia)
12/2012 - 10/2004
3Iron Overload
01/2022 - 10/2004
3Mitochondrial Diseases (Mitochondrial Disease)
12/2020 - 09/2015
3Starvation
12/2020 - 10/2011
3Hypoxia (Hypoxemia)
10/2019 - 08/2005
3Parkinson Disease (Parkinson's Disease)
05/2007 - 06/2004
2Infections
12/2021 - 01/2013
2Neurodegeneration with brain iron accumulation (NBIA)
04/2021 - 01/2019
2Neoplasms (Cancer)
12/2020 - 08/2005
2Neurodegenerative Diseases (Neurodegenerative Disease)
10/2016 - 09/2012
2Hypertrophy
01/2015 - 12/2012
2Cardiomyopathies (Cardiomyopathy)
01/2015 - 12/2012
2Sideroblastic Anemia
10/2011 - 10/2004
2Inflammation (Inflammations)
03/2010 - 03/2009
2Altitude Sickness (Mountain Sickness)
06/2009 - 06/2007
1Granuloma
12/2021
1Dystonia (Limb Dystonia)
12/2020
1Cognitive Dysfunction
12/2020
1Prostatic Neoplasms (Prostate Cancer)
12/2020
1Hyperferritinemia
04/2017
1Ovarian Cysts (Ovarian Cyst)
03/2014
1Endometriosis
03/2014
1Iron Deficiencies
12/2013
1Restless Legs Syndrome (Restless Legs)
08/2013
1Seizures (Absence Seizure)
08/2013
1Multiple Myeloma
06/2013
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
06/2013
1Cicatrix (Scar)
12/2012
1Necrosis
12/2012
1Macular Degeneration (Age-Related Maculopathy)
01/2012
1Refractory Anemia
10/2011
1Anemia
01/2007
1Kidney Neoplasms (Kidney Cancer)
08/2005
1Renal Cell Carcinoma (Grawitz Tumor)
08/2005
1Hemochromatosis (Bronze Diabetes)
12/2004
1Cardiotoxicity
04/2004
1Gliosis
07/2002

Drug/Important Bio-Agent (IBA)

32IronIBA
12/2021 - 04/2004
12Ferritins (Ferritin)IBA
04/2021 - 01/2007
11ApoferritinsIBA
12/2021 - 09/2006
8Proteins (Proteins, Gene)FDA Link
12/2020 - 06/2007
4FrataxinIBA
01/2015 - 10/2004
3Coenzyme A (CoA)IBA
01/2022 - 09/2015
2metal transporting protein 1 (ferroportin)IBA
12/2021 - 12/2004
2CalciumIBA
12/2020 - 05/2020
2Oxygen (Dioxygen)IBA
10/2019 - 06/2007
2EnzymesIBA
09/2015 - 01/2009
2MetalsIBA
01/2015 - 06/2004
2Transferrin Receptors (Transferrin Receptor)IBA
03/2014 - 08/2005
2Reactive Oxygen Species (Oxygen Radicals)IBA
10/2011 - 04/2004
2NucleotidesIBA
04/2010 - 09/2006
2MyoglobinIBA
06/2009 - 06/2007
1CytokinesIBA
12/2021
1MagnesiumIBA
12/2020
1AndrogensIBA
12/2020
1Androgen Antagonists (Antiandrogens)IBA
12/2020
1bicalutamide (Casodex)FDA LinkGeneric
12/2020
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
01/2015
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
01/2015
1ZincIBA
01/2015
1HepcidinsIBA
01/2015
1Anti-Mullerian HormoneIBA
03/2014
1Messenger RNA (mRNA)IBA
03/2014
1Pharmaceutical PreparationsIBA
06/2013
1Small Interfering RNA (siRNA)IBA
06/2013
1Bortezomib (Velcade)FDA Link
06/2013
1Toll-Like Receptor 2IBA
01/2013
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2012
1Retinaldehyde (Retinal)IBA
01/2012
1Hemoglobins (Hemoglobin)IBA
06/2007
1Peptides (Polypeptides)IBA
09/2006
1Transferrin (beta 2 Transferrin)IBA
08/2005
1Mitochondrial Proteins (Mitochondrial Protein)IBA
10/2004
1Mitochondrial DNA (mtDNA)IBA
10/2004
1NoxaeIBA
06/2004
1Doxorubicin (Adriamycin)FDA LinkGeneric
04/2004
1AnthracyclinesIBA
04/2004
1Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
07/2002

Therapy/Procedure

3Therapeutics
12/2020 - 01/2015